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Sir Alexander Fleming
Biography
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Sir
Alexander Fleming was born at Lochfield near Darvel in Ayrshire, Scotland on August 6th, 1881. He attended
Louden Moor School, Darvel School, and Kilmarnock Academy before moving to
London where he attended the London Polytechnic. He spent four years in a shipping
office before entering St. Mary's Medical School, London University. He
qualified with distinction in 1906 and began research at St. Mary's under
Sir Almroth Wright, a pioneer in vaccine therapy. He gained an M.B., B.S.,
(London), with Gold Medal in 1908, and became a lecturer at St. Mary's until
1914. He served throughout World War I as a captain in the Army Medical
Corps, being mentioned in dispatches, and in 1918 he returned to St. Mary's.
He was elected Professor of the School in 1928 and Emeritus Professor of
Bacteriology,
University of London in 1948. He was elected Fellow of the
Royal Society in 1943 and knighted in 1944.
Early in his medical life, Fleming became interested in the natural
bacterial action of the blood and in antiseptics. He was able to continue
his studies throughout his military career and on demobilization he settled
to work on antibacterial substances which would not be toxic to animal
tissues. In 1921, he discovered in «tissues and secretions» an important
bacteriolytic substance which he named Lysozyme. About this time, he devised
sensitivity titration methods and assays in human blood and other body
fluids, which he subsequently used for the titration of penicillin. In 1928,
while working on influenza virus, he observed that a mould had developed
accidentally on a staphylococcus culture plate and that the mould had created
a bacteria-free circle around itself. He was inspired to further experiment
and he found that a mould culture prevented growth of staphylococci, even
when diluted 800 times. He named the active substance penicillin.
Sir Alexander wrote numerous papers on bacteriology, immunology and
chemotherapy, including original descriptions of lysozyme and penicillin.
They have been published in medical and scientific journals.
Fleming, a Fellow of the
Royal College of Surgeons (England), 1909, and a Fellow of the Royal
College of Physicians (London), 1944, has gained many awards. They include
Hunterian Professor (1919), Arris and Gale Lecturer (1929) and Honorary Gold
Medal (1946) of the Royal College of Surgeons; Williams Julius Mickle
Fellowship, University of London (1942); Charles Mickle Fellowship,
University of Toronto (1944); John Scott Medal, City Guild of Philadelphia
(1944); Cameron Prize, University of Edinburgh (1945); Moxon Medal, Royal
College of Physicians (1945); Cutter Lecturer, Harvard University (1945);
Albert Gold Medal, Royal Society of Arts (1946); Gold Medal, Royal Society
of Medicine (1947); Medal for Merit, U.S.A. (1947); and the Grand Cross of
Alphonse X the Wise, Spain (1948).
He served as President of the
Society for General Microbiology, he was a Member of the Pontifical
Academy of Science and Honorary Member of almost all the medical and
scientific societies of the world. He was Rector of
Edinburgh University during 1951-1954, Freeman of many boroughs and
cities and Honorary Chief Doy-gei-tau of the Kiowa tribe. He was also
awarded doctorate, honoris causa, degrees of almost thirty European
and American Universities.
In 1915, Fleming married Sarah Marion McElroy of Killala, Ireland, who died
in 1949. Their son is a general medical practitioner.
Fleming married again in 1953, his bride was Dr. Amalia Koutsouri-Voureka, a
Greek colleague at St. Mary's.
In his younger days he was a keen member of the Territorial Army and he
served from 1900 to 1914 as a private in the London Scottish Regiment.
Dr Fleming died on March 11th in 1955 and is buried in St. Paul's Cathedral.
His work was responsible for the saving the lives of millions and millions
of people.
He
is honoured once a year in school when we hold a special Sir Alexander
Fleming Day.
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